Description
Product Characteristics:
IFI27
Subcellular location: Cytoplasm
Synonyms: 2310061N23Rik, FAM 14D, FAM14D, IFI 27, Interferon alpha induced 11.5 kDa protein, Interferon alpha inducible protein 27, interferon alpha-inducible protein 27, mitochondrial, Interferon inducible protein 27, interferon-stimulated gene 12, interferon-stimulated gene 12a protein, ISG 12, ISG12, ISG12(a) protein, ISG12A, IFI27_HUMAN, P27.
Target Information: Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1- CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry (By similarity)